Expired Tylenol (acetaminophen) usually is not suddenly poisonous, but it may not work as well and major health agencies advise against using it.
General safety
Most medicines, including acetaminophen, lose potency gradually after the expiration date rather than becoming acutely toxic. The U.S. FDA and manufacturers recommend not using expired medicines because effectiveness and safety are only guaranteed up to the printed date.
Specific to Tylenol
Tylenol typically has a shelf life of about 2–3 years when stored properly, and after that it may be significantly less effective (sometimes estimated around 80% potency or less). For short‑term pain or fever, a dose that is just a little past expiration is unlikely to harm you, but it might not relieve symptoms as well.
When to avoid it
You should not use expired liquid acetaminophen, especially for children, because liquids are more prone to degradation and contamination. If the product is very old, discolored, crumbling, or has an unusual smell, do not take it at all.
What to do instead
If possible, discard expired Tylenol through a medication take‑back program or follow local guidance for safe disposal and get a fresh, in‑date product. If you have already taken an expired dose and feel unwell (nausea, abdominal pain, confusion, or any worrying symptoms), contact a poison center or seek urgent medical care.
Quick rule of thumb
- Just a little past expiration, in an intact, properly stored tablet bottle: low risk but less reliable relief; replacing it is still recommended.
- Very old, liquid, or visibly changed medicine, or any use in children: do not use; talk to a doctor or pharmacist for safer options.
