how long does it take for clonidine to work

Clonidine typically starts to work within 30 to 60 minutes after taking a dose, with immediate effects such as drowsiness and sedation appearing sometimes even after the first dose. However, it may take 2 to 4 weeks for the medication to become fully effective and for noticeable improvement in symptoms, especially for conditions like high blood pressure or ADHD. For some symptoms, maximum benefits might take up to 4 to 8 weeks once the right dose is determined. Immediate-release formulations show effects on blood pressure within 1 to 2 hours, while extended-release forms take longer but last longer in the system. Regular use and dosage adjustments by a healthcare provider are important for optimal effects, and sudden discontinuation can cause dangerous side effects.