when is the first regular season nfl game

The first regular season NFL game for the 2025 season is scheduled to take place on Thursday, September 4, 2025. The game will feature the reigning Super Bowl champion Philadelphia Eagles hosting the Dallas Cowboys in the NFL Kickoff Game. This tradition typically has the defending champions hosting the opening game of the season. The game will be broadcast on NBC and Peacock at 8:20 p.m. ET.