America as a nation was founded in 1776 when the Second Continental Congress declared independence from Great Britain. The Declaration of Independence was adopted on July 4, 1776, which has since been celebrated as the founding date of the United States of America. This act marked the beginning of America as a sovereign nation distinct from British rule.
Before this, European colonization began in the late 15th and early 16th centuries, including the establishment of Jamestown, Virginia, in 1607, which was one of the first permanent English settlements in what would become the United States. Native Americans had inhabited the land for tens of thousands of years prior to European arrival.
In summary, the United States of America was officially founded on July 4, 1776, with the Declaration of Independence.