The 49ers vs Rams game on Thursday Night Football in October 2025 is available to watch live on Amazon Prime Video and also free on Twitch. Fans in the local markets of Los Angeles and San Francisco can watch the game on their local Fox stations—Fox 11 (KTTV) in Los Angeles and Fox 2 (KTVU) in San Francisco. The game kicks off at 8:15 p.m. ET (5:15 p.m. PT) at SoFi Stadium in Inglewood, California. For viewers outside the local markets, a subscription to Amazon Prime or Prime Video is needed, but the game is also streamable on the NFL+ app (with some device restrictions).
