are there male calico cats

30 minutes ago 1
Nature

Direct answer: Yes, male calico cats exist, but they are extremely rare. Most calico cats are female due to the way coat color genes are linked to the X chromosome. Male calicos usually occur only when a genetic anomaly is present, most commonly an extra X chromosome (XXY, known as Klinefelter syndrome) or in rare cases as a genetic chimera. In these cases, the male cat can display the calico tri-color pattern, but such cats are typically sterile and may have associated health issues. Estimates commonly cited put the frequency at about 1 in 3,000 calico cats being male. If you’re considering ownership or care, expect unique genetic considerations and possible health needs, and consult a veterinarian for guidance.