at which site do new aminoacyl trnas enter the ribosome during elongation?

New aminoacyl tRNAs enter the ribosome at the A site during elongation. This is where the incoming aa-tRNA, delivered as a ternary complex with EF-Tu (in bacteria) or its eukaryotic counterpart, binds to the codon presented by the mRNA, pairing with the codon to select the correct amino acid for incorporation into the growing polypeptide. After correct codon-anticodon pairing, the ribosome catalyzes peptide bond formation and proceeds with translocation, moving the tRNAs into hybrid states and advancing to the next codon. This remains consistent across prokaryotic and eukaryotic systems, with the A site serving as the entry point for the aminoacyl-tRNA during each elongation cycle.