The main cast of "The Big Bang Theory" includes:
- Johnny Galecki as Dr. Leonard Hofstadter
- Jim Parsons as Dr. Sheldon Cooper
- Kaley Cuoco as Penny
- Simon Helberg as Howard Wolowitz
- Kunal Nayyar as Dr. Raj Koothrappali
- Melissa Rauch as Dr. Bernadette Rostenkowski Wolowitz
- Mayim Bialik as Dr. Amy Farrah Fowler
- Kevin Sussman as Stuart Bloom
- Sara Gilbert as Dr. Leslie Winkle
- Laura Spencer as Dr. Emily Sweeney
These actors made up the primary ensemble cast throughout the show's run from 2007 to 2019, with some characters introduced later into the series such as Amy Farrah Fowler and Bernadette Wolowitz.
