It is generally safe to drink alcohol after getting a flu shot, but it is advised to do so in moderation. Avoiding alcohol for at least several hours or up to 24 hours after the vaccination might be beneficial to allow the immune system to respond optimally. Excessive alcohol consumption can suppress immune cell activity, reduce the effectiveness of the vaccine, worsen side effects, and prolong recovery. Moderate drinking (1 drink or less per day for women and 2 or less for men) is usually considered acceptable, but heavy drinking should be avoided especially in the first two weeks post-vaccination. If experiencing side effects like fatigue or muscle soreness, it may be best to avoid alcohol until those resolve. Staying hydrated and avoiding alcohol-related dehydration after the flu shot is also recommended.
