You can usually drink small amounts of alcohol while on spironolactone, but it is not risk‑free and depends a lot on why you are taking it and your overall health.
Key points
- If you take spironolactone for liver disease or serious heart problems, guidelines say you should generally avoid alcohol completely because alcohol can worsen these conditions.
- When alcohol is allowed (for things like acne, mild blood pressure issues, or hormonal problems), sticking to low or moderate intake is advised (for example, no more than 1–2 standard drinks on a day you choose to drink, and staying within weekly guideline limits).
Possible risks when mixing
- Both spironolactone and alcohol can lower blood pressure and cause dizziness, lightheadedness, or even fainting, especially when standing up quickly.
- Both act as diuretics, so they make you pee more and can increase the risk of dehydration and feeling weak or unwell if you do not drink enough water.
Safety tips if you choose to drink
- Ask the prescriber or pharmacist who manages your spironolactone whether alcohol is safe for you personally, especially if you have kidney, liver, or heart disease, or high potassium.
- If you drink:
- Limit to a small amount (1–2 drinks max on an occasion).
- Drink slowly, with food, and have plenty of water to reduce dehydration and dizziness.
* Stop and seek medical advice urgently if you notice fainting, severe dizziness, chest pain, palpitations, or confusion.
If you ever stop spironolactone, many sources suggest waiting several days (around 3–4 days) for the medicine to clear before returning to heavier drinking, but this should still be confirmed with your own clinician.
