It is generally safe to drink alcohol in moderation while taking over-the- counter ibuprofen, but doing so increases the risk of side effects such as stomach irritation, gastrointestinal bleeding, kidney damage, and liver problems. Moderation means no more than two drinks per day for men and one for women. People with underlying conditions like liver or kidney disease, or a history of gastrointestinal bleeding, should be especially cautious or avoid combining the two. It is recommended to avoid drinking alcohol for at least 4 to 10 hours after taking ibuprofen to minimize risks. If ibuprofen is taken regularly or in higher doses, the risks increase significantly. Symptoms like persistent stomach pain, black stools, or swelling should prompt immediate medical attention. Overall, occasional moderate alcohol consumption with occasional ibuprofen use is usually not harmful, but caution and moderation are key.
