Papaya seeds are edible and contain various nutrients with potential health benefits such as antioxidants, fiber, and compounds that may support digestion, liver and kidney health, and fight parasites. However, eating papaya seeds should be done with caution and in moderation due to potential risks. Studies, mainly in animals, show that high or prolonged consumption of papaya seeds may cause liver damage and toxicity and may reduce male fertility by affecting sperm count and motility. The seeds also contain trace amounts of cyanide and compounds like benzyl isothiocyanate which could be harmful in large doses. It is generally advised not to consume papaya seeds if pregnant or trying to conceive. Consuming small quantities occasionally, such as 5-10 seeds swallowed whole or a small amount of powdered seeds, is considered safer. Consulting a healthcare professional is recommended before making papaya seeds a regular part of the diet.