The main cast of the TV series "Lost" includes:
- Matthew Fox as Dr. Jack Shephard, the protagonist and surgeon.
- Evangeline Lilly as Kate Austen, a fugitive.
- Jorge Garcia as Hugo "Hurley" Reyes, an unlucky lottery winner.
- Josh Holloway as James "Sawyer" Ford, a con man.
- Ian Somerhalder as Boone Carlyle, chief operating officer of his mother's wedding business.
- Maggie Grace as Shannon Rutherford, Boone's stepsister and a former dance teacher.
- Harold Perrineau as Michael Dawson, a construction worker and aspiring artist.
- Malcolm David Kelley as Walt Lloyd, Michael Dawson's young son.
- Terry O'Quinn as John Locke, a mysterious figure.
- Naveen Andrews as Sayid Jarrah, a former Iraqi Republican Guard.
- Emilie de Ravin as Claire Littleton, a young Australian mother-to-be.
- Yunjin Kim as Sun-Hwa Kwon, daughter of a wealthy Korean businessman.
- Daniel Dae Kim as Jin-Soo Kwon, Sun's husband and enforcer for her father.
- Dominic Monaghan as Charlie Pace, an English ex-rock star and drug addict.
- Henry Ian Cusick as Desmond Hume, a former Scottish soldier.
- Michael Emerson as Ben Linus, the manipulative leader of the Others.
- Elizabeth Mitchell as Juliet Burke, a fertility doctor and member of the Others.
- Adewale Akinnuoye-Agbaje as Mr. Eko, a Nigerian fake Catholic priest and former criminal.
- Michelle Rodriguez as Ana Lucia Cortez, an airport security guard and former police officer.
- Cynthia Watros as Libby Smith, a purported clinical psychologist.
This cast brought diverse characters and multicultural backgrounds to the series, which ran for six seasons from 2004 to 2010. Several characters were written out over the course of the show, and new characters were introduced as the story progressed.