cetylpyridinium chloride review

1 year ago 31
Nature

Cetylpyridinium chloride is a quaternary ammonium salt with broad-spectrum antiseptic properties. Its salt form is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is also used in topical anti-infective products and as a pharmaceutical preservative. Here are some additional details about cetylpyridinium chloride:

Positive:

  • Works against harmful bacteria within dental plaque
  • Mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis

Negative:

  • Hazard class: Acute toxicity, oral, category 4; Skin corrosion/irritation, category 2; Serious eye damage/eye irritation, category 1; Acute toxicity: inhalation, category 2; Specific target organ toxicity, single exposure, respiratory tract irritation, category 3
  • Use restrictions (moderate), Neurotoxicity (low), Endocrine disruption (low), and Non-reproductive organ system toxicity (moderate)

Ingredients or materials:

  • Cetylpyridinium chloride is a chloride salt and an organic chloride salt
  • It contains a cetylpyridinium
  • Chemical formula: C21H38ClN

It is important to note that no readily available data regarding the volume of distribution, protein binding, or clearance of cetylpyridinium chloride is available.