Clotrimazole is an antifungal agent that is used to treat various skin infections, including athletes foot, jock itch, and ringworm. However, according to the FDA, Clotrimazole and Betamethasone Dipropionate Cream or Lotion is not recommended for use in diaper rash. The safety of Clotrimazole and Betamethasone Dipropionate Cream or Lotion has not been demonstrated in the treatment of diaper dermatitis, and adverse events consistent with corticosteroid use have been observed in patients treated with Clotrimazole and Betamethasone Dipropionate Cream, USP for diaper dermatitis. Therefore, the use of Clotrimazole and Betamethasone Dipropionate Cream or Lotion in the treatment of diaper dermatitis is not recommended. Additionally, Clotrimazole Cream 1% contains cetostearyl alcohol and benzyl alcohol as excipients. While Clotrimazole is generally well-tolerated, some adverse reactions have been reported with use of clotrimazole topical solution in a clinical trial, including drying effect, maculopapular rash, and increased sweating.