does tirzepatide make you tired

Yes, tirzepatide can make you feel tired. Fatigue is a known but relatively uncommon side effect that affects some people taking tirzepatide, including its brand names Zepbound and Mounjaro. The tiredness is often temporary and tends to improve as the body adjusts to the medication. The fatigue may result from several factors including reduced calorie intake due to appetite suppression, dehydration caused by side effects like nausea or diarrhea, and changes in blood sugar processing. Staying hydrated, eating balanced meals, and getting enough rest can help manage this fatigue, which often resolves within a few weeks of starting treatment or dose escalation.