Efudex cream is a topical cytostatic preparation used for the treatment of superficial pre-malignant and malignant skin lesions. It contains 5% w/w fluorouracil as the active ingredient. Here are some details about Efudex cream:
Positive effects:
- Studies with the active ingredient of Efudex, 5-fluorouracil, have shown positive effects in in vitro tests for mutagenicity and on impairment of fertility.
Negative effects:
- The normal pattern of response to Efudex treatment includes early and severe inflammatory phases characterized by erythema, which may become intense and blotchy, a necrotic phase characterized by skin erosion, and finally healing when epithelialization occurs.
- Treatment effects can sometimes be more severe and include pain, blistering, and ulceration.
- Efudex cream may contain inactive ingredients that can cause allergic reactions or other problems.
Ingredients:
- Active ingredient: 5% w/w fluorouracil.
- Excipients: For the full list of excipients, see section 6.1 of the Summary of Product Characteristics.
It is important to keep a written list of all prescription and nonprescription medicines, as well as any products such as vitamins, minerals, or other dietary supplements, that you are taking. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
