Product Details:
- Name: Efudix Cream
- Active Ingredient: 5% w/w fluorouracil
- Pharmaceutical Form: White, opaque cream
- Group: Anti-cancer medicines (also called antineoplastic or cytotoxic)
Positive Effects:
- Studies with the active ingredient of Efudix, 5-fluorouracil, have shown positive effects in in vitro tests for mutagenicity and on impairment of fertility.
- Efudix is a topical cytostatic preparation which exerts a beneficial therapeutic effect on neoplastic and pre-neoplastic skin lesions while having less effect on normal cells.
Negative Effects:
- The normal pattern of response to Efudix treatment includes early and severe inflammatory phases (typically characterized by erythema, which may become intense and blotchy), a necrotic phase (characterized by skin erosion), and finally healing (when epithelialization occurs).
- These treatment effects can sometimes be more severe and include pain, blistering, and ulceration.
- Adverse effects of Efudix may include pain, pruritus, headache, insomnia, irritability, rash, photosensitivity, leukocytosis, thrombocytopenia, birth defects, burning, inflammation, miscarriage, herpes simplex, allergic contact dermatitis, telangiectasia, hyperpigmentation (rare), and scarring (rare).
Ingredients or Materials:
- Efudix cream contains 5% w/w fluorouracil as the active ingredient.
- For the full list of excipients, see section 6.1 of the products Summary of Product Characteristics.
