Fluticasone propionate is a synthetic corticosteroid (glucocorticoid) used mainly to reduce inflammation in the airways, nose, and on the skin. It is found in many inhalers, nasal sprays, and topical creams or ointments used for asthma, allergies, and certain skin conditions.
What it is
Fluticasone propionate is a highly potent glucocorticoid that works by binding to glucocorticoid receptors and decreasing the production of inflammatory mediators in tissues such as the lungs, nasal mucosa, and skin. Clinically, this leads to less swelling, mucus production, and irritation in the treated area.
Main medical uses
Common uses include:
- Inhalers for long‑term control of asthma and sometimes COPD.
- Nasal sprays for allergic and non‑allergic rhinitis and nasal polyps.
- Topical creams/ointments for inflammatory skin diseases such as eczema and psoriasis.
Common side effects
Side effects depend on the route:
- Inhaled: throat irritation, cough, oral thrush, hoarseness.
- Nasal: nosebleeds, nasal irritation, sore throat, headache.
- Topical: skin thinning or irritation with prolonged/high‑potency use.
Systemic steroid effects (such as adrenal suppression, growth effects in children, or osteoporosis) are uncommon at usual doses but can occur, especially with long‑term high‑dose use.
Key safety points
- Rinse the mouth after inhaled doses to reduce the risk of oral thrush.
- Use the lowest effective dose for the shortest time needed to control symptoms.
- People with frequent infections, glaucoma, cataracts, or on other steroids should discuss risks and monitoring with a healthcare professional.
- It is not a rescue medicine for sudden asthma attacks; a separate fast‑acting bronchodilator is required for acute symptoms.
If you share how you are using (or plan to use) fluticasone propionate—nose, lungs, or skin—more specific dosing and safety guidance can be provided.
