The most recent notable matchup between Houston and Duke in men's college basketball was in the 2025 NCAA Men's Final Four. Houston defeated Duke with a close score of 70-67. This game featured a strong comeback by Houston in the final minutes and showcased Houston's experience in close games against Duke's talent. The victory allowed Houston to advance to the National Championship Game after their tough battle against Duke, which was a highly competitive and physical game held in San Antonio. Previously, the two teams split their last two matchups with Duke winning 54-51 in 2024 and Houston winning 70-67 in 2025. Both teams finished the season with strong records leading into the tournament. In summary, Houston won the recent key Final Four game against Duke 70-67 in a dramatic and physically intense contest, advancing Houston to the championship round.
