how did matthew perry die

Matthew Perry died on October 28, 2023, at the age of 54, from the acute effects of ketamine, which led to an accidental overdose. The autopsy revealed that he had high levels of ketamine in his blood, sufficient to cause loss of consciousness and respiratory depression. Perry was found face down in the heated end of his pool, and drowning was listed as a secondary contributing factor to his death. Other contributing factors included coronary artery disease and the effects of buprenorphine, a medication used to treat opioid addiction. The ketamine in his system was not from his last ketamine infusion therapy session, which had occurred about 1.5 weeks before his death, as ketamine is typically metabolized within hours. Perry had been receiving ketamine infusion therapy for depression and anxiety, but the exact method of intake on the day of his death was unknown. His death was ruled an accident. Five people have been charged in connection with helping him acquire lethal doses of ketamine