Sepsis is contracted when an existing infection in the body triggers an extreme immune system response. It is usually caused by bacterial infections such as pneumonia, abdominal infections, and urinary tract infections. Fungal and viral infections, including COVID-19 and the flu, can also cause sepsis. Any infection, especially if severe or untreated, can lead to sepsis if the infection spreads into the bloodstream and causes widespread inflammation. Risk factors include being very young or old, having a weakened immune system, recent surgery, or having invasive devices like catheters. Infections can enter the body through wounds, open fractures, bug bites, or contaminated water or food (like raw oysters), which can then lead to sepsis if the infection is severe or uncontrolled. Sepsis itself is not contagious; it is the infection that causes it that gets into the body.