Mounjaro (active ingredient tirzepatide) works by activating two receptors in the body known as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones are involved in digestion, appetite regulation, and blood sugar control. Here's how Mounjaro works:
- It mimics GLP-1 and GIP hormones, which signal the pancreas to release more insulin when needed, lowering blood sugar levels.
- It decreases the production of glucagon (a hormone that raises blood sugar), helping prevent high blood sugar.
- It slows gastric emptying, meaning food moves more slowly from the stomach to the intestines.
- It reduces appetite by activating receptors in the brain and stomach that make you feel full sooner, leading to lower food intake and weight loss.
- It improves insulin sensitivity, helping the body's cells take in glucose from the blood more effectively.
- It lowers the amount of sugar produced by the liver.
These combined effects help lower blood sugar and promote weight loss in people with type 2 diabetes or obesity. Mounjaro is given as a once-weekly injection and is designed to support blood sugar control and reduce appetite and food intake.
