The mucus plug is typically lost sometime after 37 weeks of pregnancy, but it can come out earlier in some cases. Losing the mucus plug is a sign that the cervix is beginning to dilate and thin in preparation for labor. This can happen days or even a few weeks before labor starts. Occasionally, it may be lost even earlier due to preterm labor or cervical changes, and in such cases, it's important to consult a healthcare provider. Some people lose the mucus plug gradually in small pieces, while others lose it all at once. Losing the mucus plug does not guarantee that labor will start immediately; it may be hours, days, or even weeks away.
If the mucus plug is lost before 37 weeks, it could be a sign of preterm labor, so medical advice should be sought promptly. On the other hand, losing it anytime after 37 weeks is generally a normal part of labor preparation.