Weight loss on Ozempic (semaglutide) is generally gradual and varies by individual, dose, and lifestyle factors. Here are the key points on how fast you can lose weight with Ozempic:
- Typical weight loss rate: Clinical studies show an average weight loss of about 1 to 2 pounds per week, which can add up to roughly 5 pounds per month
. Over longer periods, this can translate to a 10-15% reduction in body weight over about a year
- Timeline for noticeable effects: Some users may feel appetite suppression as early as the first day, but noticeable weight loss usually starts after a few weeks and becomes more significant around 8 to 12 weeks as the dose is increased
- Average weight loss in studies: Over 26 to 40 weeks, patients lost on average 12 to 14 pounds, with some losing up to 30 pounds in about 6 months
. The amount of weight lost depends on the dose, with higher doses (up to 2 mg weekly) generally producing more weight loss
- Factors influencing weight loss: Weight loss depends on starting weight, diet, exercise, dose of Ozempic, and other medications. Ozempic works by reducing appetite and slowing digestion, helping you eat less
- Comparison to other drugs: Ozempic and similar GLP-1 receptor agonists lead to more substantial weight loss than older medications, with typical reductions of 15-20% body weight over about 68 weeks when combined with lifestyle changes
In summary, you can expect to lose about 1-2 pounds per week on Ozempic, with more noticeable results after several weeks as the dose is increased. Sustained weight loss of 10-15% of body weight over many months is common when combined with diet and exercise.
