After defrosting chicken, it should be cooked within 1 to 2 days if thawed in the refrigerator. If defrosted using faster methods such as a cold water bath or microwave, it should be cooked immediately after thawing. This is because these methods can allow bacteria to grow if the chicken is left too long before cooking. Cooking defrosted chicken promptly ensures food safety and prevents the risk of foodborne illness. Always cook chicken to an internal temperature of 165°F (74°C) to ensure it is safe to eat.