how long does endone take to work

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Endone, which contains oxycodone, typically starts to work within about 30 to 60 minutes after taking it. The pain relief effects begin within that time frame and last for about 4 to 6 hours for the immediate-release form like Endone. It is advised to take Endone as prescribed, usually every six hours, and after food or with milk to optimize its effects and reduce stomach upset.

Key Information about Endone (Oxycodone)

  • Onset of action: 30 to 60 minutes for immediate-release tablets like Endone.
  • Duration: Pain relief lasts approximately 4 to 6 hours.
  • Best taken after meals or with milk to reduce potential stomach irritation.
  • Dosage typically prescribed as one tablet every six hours, but follow the doctor’s instructions.

This timing applies to standard immediate-release oxycodone formulations such as Endone, not slow-release oxycodone variants which take longer to start working.