how long does it take for excedrin to work

Excedrin typically starts working within 20 to 30 minutes after ingestion for many users, with most relief occurring between 30 minutes to 1 hour. The exact time for it to take effect can vary based on individual physiology, severity of the headache or migraine, metabolism, and factors like whether the medication is taken on an empty or full stomach. For some, relief might begin as early as 15 minutes, but for others, it could take up to an hour or more. The effects of Excedrin usually last for about 4 to 6 hours. It is important to follow the recommended dosage and not to exceed it for safety reasons.