Famotidine typically begins to work within one hour of oral administration, with peak effectiveness reached between one to three hours. Its acid- suppressing effects can last for up to 10 to 12 hours. When administered intravenously, famotidine acts faster, reaching peak effect within about 30 minutes. This makes famotidine effective for quick relief of acid-related conditions like heartburn, gastroesophageal reflux disease (GERD), and stomach ulcers.
