Humira (adalimumab) can start working as soon as 2 weeks after starting treatment for some people, but it may take 3 to 6 months or longer for others to notice significant improvement depending on the condition being treated and individual response. For example, in rheumatoid arthritis, improvement may be seen after about 6 months, while in plaque psoriasis, about 75% skin clearance is often seen after 4 months. Regular reviews with a healthcare provider occur within weeks to months to assess effectiveness and adjust treatment if needed.
