Losartan typically begins to work within 1 hour of administration, with initial blood pressure reduction effects observable within a few hours. Peak effects usually occur within 3 to 6 hours after each dose. However, the full therapeutic antihypertensive effect of losartan may take 3 to 6 weeks to be fully realized. This longer timeframe allows for blood pressure stabilization and maximum benefit from the medication. It is important to continue taking losartan as prescribed even if immediate effects are not felt, as the medication works progressively over time.
