Muscle relaxers generally start to take effect within 30 minutes to one hour after ingestion. The peak effectiveness usually occurs between 1 to 3 hours depending on the specific medication. The duration of their effects can range from 4 to 24 hours based on the type of muscle relaxer and individual factors such as metabolism and dosage. Here are specifics for common muscle relaxers:
- Cyclobenzaprine (Flexeril) starts working in about 30 to 60 minutes, with peak effects at 4 to 8 hours and lasting up to 24 hours.
- Methocarbamol takes about 30 minutes to start working, peaking in 1 to 2 hours, and lasting 4 to 6 hours.
- Carisoprodol begins effect in 30 minutes, peaks within 1 to 2 hours, and lasts 4 to 6 hours.
- Tizanidine takes 1 to 2 hours to work, with effects lasting 4 to 6 hours.
- Baclofen works in about 1 hour and peaks within 2 to 3 hours, lasting 4 to 8 hours.
The time it takes for muscle relaxants to work can be influenced by individual metabolism, age, organ function, dosage, drug interactions, and formulation. Extended-release versions tend to take effect slower but last longer. Overall, pain relief and muscle relaxation usually begin within the first hour after taking the medication, with full effects sometimes taking several days of use to optimize for some drugs like cyclobenzaprine extended-release forms.
