Spironolactone typically starts showing improvement in acne within about 4 to 8 weeks, with significant results often seen by 3 months. Full benefits can take 3 to 5 months of consistent use, and sometimes up to 6 months for acne to fully settle. The timeline varies depending on factors like dosage, consistency, and the severity of acne. Common dosages range from 50 to 200 mg per day, with many people starting to notice fewer breakouts and reduced oiliness within weeks. Initial skin adjustment phases may include some purging or dryness. Long-term use (6-12 months) is often recommended to maintain results and is generally considered safe.
