how long does it take for tramadol to work

Tramadol typically starts to work within about 30 to 60 minutes after taking it, especially in its fast-acting forms such as drops, injections, and some tablets or capsules. The pain relief usually peaks around 2 to 3 hours after taking immediate-release tramadol and lasts for about 4 to 6 hours. Extended- release tramadol takes longer to start working, about a day or two, but provides longer-lasting pain relief, up to 12 to 24 hours, and is taken once daily. The onset and duration can also be influenced by factors like metabolism, dose, and whether tramadol is taken with food.