Hydroxyzine typically starts to work within about 15 to 60 minutes after a dose, with many people noticing relief of symptoms (such as allergy itching or anxiety) within 30 minutes to 2 hours. The full effect often develops over 1–2 hours, and the sedative or calming effects can last around 4–6 hours, though duration may vary by individual, dose, and formulation. Always follow your healthcare provider’s instructions for dosing and timing, and contact a clinician if you don’t notice an effect within a reasonable time or if side effects are concerning. [tool-derived context]
