Pepto Bismol usually takes about 30 to 60 minutes to start working and provide relief from symptoms like nausea, heartburn, indigestion, upset stomach, and diarrhea. If relief is not felt after the first dose, another dose can be taken after 30 to 60 minutes, but the maximum should not exceed 8 doses in 24 hours. The medication works by forming a protective coating in the stomach and intestines, reducing inflammation, killing germs that cause diarrhea, and counteracting excess gastric acid.
