how long is tylenol effective

Tylenol (acetaminophen) typically provides relief for about 4 to 6 hours for regular formulations, with extended-release/long-acting versions lasting roughly 8 hours or more. Onset of relief generally occurs within 30 minutes to 1 hour for most oral forms, though this can vary by formulation (liquid, dissolvable powder, chewable tablet, etc.) and by individual factors such as stomach contents and liver function. Fever reduction may take a bit longer than pain relief. Always adhere to the dosing instructions on the label or your clinician’s guidance, and do not exceed the recommended daily limit (for most adults, 4000 mg per day, though certain individuals may need lower limits). If symptoms persist beyond a few days, worsen, or you have liver disease, regularly consume alcohol, or take multiple acetaminophen-containing products, seek medical advice.