The safe daily intake of biotin for adults is generally around 30 micrograms (mcg) per day, according to recommendations. Most people get enough biotin through their diet and internal production, and biotin deficiency is rare. There is no established upper limit for biotin intake because it is a water- soluble vitamin, and excess amounts are typically excreted in the urine. Higher doses, such as up to 5 milligrams (5000 mcg) or even in the range of 10-50 milligrams (10,000-50,000 mcg), have been used in specific cases like biotin deficiency without reported toxicity. Some studies indicate doses as high as 300 mg per day are likely safe for up to 6 months, but such high doses should only be taken under medical supervision. Biotin can interfere with certain lab tests, so it is important for individuals taking supplements, especially in higher doses, to inform their healthcare provider. Summary of key points:
- Recommended daily intake for adults: about 30 mcg.
- Pregnant and breastfeeding women may need about 30-35 mcg per day.
- No known toxic upper limit; excess biotin is excreted.
- High doses used therapeutically can be in milligrams, but only under supervision.
- High doses may interfere with lab tests.
These dosage guidelines provide a safe framework for daily biotin intake while acknowledging that higher doses may be necessary for certain medical conditions or deficiencies, always under healthcare professional advice.