Zepbound without insurance costs vary depending on the form and dosage. For single-dose vials purchased through LillyDirect Self Pay Pharmacy, the costs are approximately $349 for a 2.5mg vial and $499 for a 5mg vial. The list price for a monthly supply of Zepbound pens (four weekly injections) is around $1,086 to $1,507, with some variation based on pharmacy and discounts. Using single-dose vials with syringes can reduce the cost compared to pre-filled pens. Some programs like the Zepbound Self Pay Journey Program offer discounts on higher doses if refilled timely. The average monthly cost without insurance for the pre-filled pens is roughly $1,507, about $375 per dose, with a yearly cost exceeding $19,000. In summary:
- Single-dose vial (through LillyDirect):
- 2.5mg vial: $349
- 5mg vial: $499
- Pre-filled pens monthly supply (4 pens): $1,086 to $1,507
- Discounts available through manufacturer programs may lower costs for the single-dose vials and certain doses.
This pricing reflects the status as of mid-2025 and may vary by pharmacy or discounts available.
