The average amount of nicotine in a single cigarette is typically around 10 to 12 milligrams (mg). However, not all of this nicotine is absorbed by the smoker. Usually, only about 1.1 to 1.8 mg of nicotine is actually inhaled and absorbed into the bloodstream from one cigarette. The nicotine content can vary significantly depending on the brand and type of cigarette, with some cigarettes containing as little as 6 mg and others as much as 28 mg of nicotine before burning, but the bioavailable amount remains roughly around 1 to 1.8 mg per cigarette smoked.