The maximum recommended dosage of ondansetron varies depending on the form and the condition being treated:
- For oral ondansetron, the maximum dose is typically 24 mg per day. This is commonly given as 8 mg doses taken multiple times per day depending on treatment needs (e.g., chemotherapy, radiation, post-surgery).
- For intravenous (IV) ondansetron, the maximum dose is usually 16 mg per dose , often given as 0.15 mg/kg per dose at intervals, not exceeding 32 mg in 24 hours. The first dose is often given 30 minutes before chemotherapy.
- If liver impairment is present, lower maximum doses are recommended (e.g., 8 mg per 24 hours).
- The exact dosage and schedule should always be followed as prescribed by a doctor, as it depends on the specific treatment and patient factors.
In summary, for most adults, the usual maximum oral dose is 24 mg per day, and the maximum IV dose is 16 mg at one time, not exceeding 32 mg total in 24 hours, but the specific dose should always be tailored and prescribed by a healthcare professional to suit individual needs and conditions. Please consult a healthcare provider for personalized and safe dosing instructions.
