On Ozempic (semaglutide), weight loss varies depending on dose, individual factors, and lifestyle, but clinical studies and reports provide a general range:
- Average weight loss is about 15 pounds (6.4 to 6.9 kg) over roughly 40 to 68 weeks, which corresponds to around 15-20% of starting body weight in some cases
- In a 40-week study, patients lost an average of 14 lbs (6.4 kg) on the 2 mg weekly dose compared to placebo
- Some people lose about 1-2 pounds per week, which could translate to around 4-8 pounds per month
- After 3 months, average weight loss can be around 5.9% of body weight, increasing to about 10.9-12.1% by 6 months depending on dose
- Higher doses (1.7 to 2.4 mg semaglutide) tend to produce greater weight loss than lower doses
- There are reports of some individuals losing up to 30% of their body weight, though this is less common and represents the high end of outcomes
- Weight loss with Ozempic is enhanced by healthy diet and exercise; it works by reducing appetite and slowing digestion, helping you feel fuller longer
It’s important to note Ozempic is FDA-approved primarily for type 2 diabetes, not specifically for weight loss; for weight loss, a related drug Wegovy (higher-dose semaglutide) is approved. Individual results vary widely based on starting weight, dose, lifestyle, and other medications
. In summary, expect around 10-15% weight loss over 6-12 months with Ozempic, with some variability. Sustained weight loss depends on combining the medication with lifestyle changes.
