Naproxen dosage frequency depends on the condition being treated and the formulation used. For immediate-release naproxen sodium tablets, the common dosing is 550 mg initially, followed by 275 mg every 6 to 8 hours as needed, or 550 mg every 12 hours. The maximum recommended daily dose usually should not exceed 1375 mg initially and thereafter not more than 1100 mg per day for pain or inflammation. Over-the-counter naproxen is typically taken as 220 mg every 8 to 12 hours while symptoms persist, with a possible initial dose of 440 mg if needed. Extended-release tablets are usually taken once daily, with a maximum dose of 1000 to 1500 mg per day for a limited time. It is important to follow the specific dosing instructions on the prescription or packaging and to not exceed the recommended dose or frequency. In summary, naproxen can generally be taken every 6 to 12 hours depending on the dose and formulation, with a maximum daily limit to avoid overdose or side effects. Consulting a doctor or pharmacist for exact dosing for individual conditions is advisable. References:
- Immediate release: 275 mg every 6 to 8 hours or 550 mg every 12 hours; max 1375 mg initial daily dose, then not more than 1100 mg/day
- Over the counter: 220 mg every 8 to 12 hours, may take 440 mg once in the first hour if needed
- Extended-release: usually once daily, max 1000-1500 mg/day for limited time
- Importance of following directions and consulting a doctor for long-term use
