Ozempic (semaglutide) is typically taken once a week. The usual starting dose is 0.25 mg injected once weekly for the first four weeks. After this initial period, the dose is usually increased every four weeks—for example, moving to 0.5 mg weekly, then 1 mg weekly, and potentially up to a maximum dose of 2 mg once weekly depending on individual tolerance and treatment goals. It is important to administer it on the same day each week, but the time of day can be flexible, with or without food. This weekly dosing schedule helps minimize side effects while optimizing the medication's benefits. The typical titration schedule looks like this:
- Weeks 1–4: 0.25 mg once weekly
- Weeks 5–8: 0.5 mg once weekly
- Weeks 9–12: 1 mg once weekly
- Week 13 and beyond: up to 2 mg once weekly
This schedule allows the body to adjust gradually to the medication.
