The optimal frequency to brush a dog's teeth is daily, as it helps remove bacteria and debris before damage occurs. If daily brushing is not practical, brushing at least 3-4 times a week can significantly improve dental health, while brushing once a week provides minimal benefits. Some veterinarians recommend brushing at least 2-3 times per week to prevent serious dental disease. Additionally, professional dental cleanings once a year are also important for comprehensive oral care. Starting early and making brushing a regular positive part of a dog's routine is beneficial for their long-term dental health.