how serious is crohn's-disease

18 hours ago 2
Nature

Crohn's disease is a serious, chronic inflammatory condition of the gastrointestinal tract that can range from mild to severe in its impact. It is a progressive disease, meaning it can worsen over time, causing complications like strictures (intestinal narrowing), fistulas (abnormal connections between organs), abscesses (localized infections), and potentially life-threatening conditions if left untreated. Symptoms typically include diarrhea, abdominal pain, weight loss, and in severe cases, persistent vomiting, high fever, and intestinal obstruction. While Crohn's disease itself is not usually fatal, its complications—such as severe infections, colorectal cancer, bowel obstruction, or perforation—can be life-threatening without proper management. Effective treatment and regular medical care can help control symptoms and reduce the risk of severe complications, allowing most people to lead active lives despite the disease.