Squamous cell carcinoma (SCC) is a serious form of skin cancer that can be very treatable when detected early, with a high cure rate of around 99% if treated promptly. However, it becomes more serious if left untreated or if it grows large or invades deeper tissues. At that point, SCC can spread (metastasize) to lymph nodes and distant organs, posing a significant health risk and lowering survival rates. The seriousness of SCC depends on certain risk factors like tumor size, depth of invasion, and whether it has spread to nerves, blood vessels, or lymph nodes. High-risk SCCs can be more aggressive, with higher chances of recurrence and metastasis. If SCC metastasizes, the five-year survival rate decreases to less than 50%. Advanced SCC can invade muscles, nerves, and bones, causing pain, disfigurement, and functional impairment. Treatment usually involves surgery (such as Mohs surgery) that has a very high success rate when tumors are removed early. In advanced cases, other treatments like radiation or immunotherapy may be needed. Early detection and treatment are critical to preventing serious complications and improving outcomes. In summary, squamous cell carcinoma is serious but highly manageable if treated early. If neglected, it can become life-threatening due to local tissue invasion and metastasis. Regular skin checks and prompt treatment of suspicious lesions are essential.
