The Depo-Provera shot can start affecting menstrual periods soon after the first injection, but the timeline for periods stopping varies among individuals. Typically, many women experience irregular bleeding or spotting within the first couple of months. Over time, especially after two to three injections (about 6 to 9 months), periods may become very light or stop completely because the shot thins the uterine lining. About 50% of women using Depo for a year experience their periods stopping entirely, a condition called amenorrhea, which is not harmful and can have benefits such as reduced cramps and lower risk of anemia.
In summary:
- Irregular bleeding or spotting may start within the first months.
- Many women see a reduction in bleeding within 3 to 6 months.
- Complete stopping of periods is common after 6 to 12 months of use.
- About half of all users experience no periods after one year on Depo.
This timing can vary because Depo works by stopping ovulation and thinning the uterine lining, which gradually changes menstrual bleeding patterns.
