Minoxidil is generally considered safe when used as directed, particularly as a topical treatment for hair loss. However, it may cause some side effects including scalp irritation, unwanted hair growth in areas other than the scalp, and in rare cases, serious allergic reactions or cardiovascular symptoms such as rapid heartbeat or dizziness. People with certain health conditions, pregnant or breastfeeding women, children under 18, or those allergic to minoxidil or ingredients in the product should avoid using it. Long-term use is usually safe if the recommended dosage is not exceeded, but systemic side effects remain a rare possibility, especially if used excessively. It is important to follow the application instructions and consult a healthcare provider if adverse symptoms occur.