Luliconazole cream, also known by its brand name LUZU, is a topical antifungal medication used to treat fungal infections such as interdigital tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum and Epidermophyton floccosum. Here are some details about Luliconazole cream:
- Active ingredient: Luliconazole, an azole antifungal agent.
- Chemical structure: (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile.
- Molecular formula: C14H9Cl2N3S2.
- Molecular weight: 354.28.
- Enantiomer: Luliconazole is the R enantiomer and contains one chiral center. The double bond adjacent to the dithiolane group is in the E configuration.
- Dosage strength: Luliconazole Cream, 1% contains 10 mg of luliconazole per gram of cream.
- Inactive ingredients: Benzyl alcohol, butylated hydroxytoluene, cetostearyl alcohol, isopropyl myristate, medium-chain triglycerides, methylparaben, polysorbate 60, propylene glycol, purified water, and sorbitan monostearate.
- Mechanism of action: The exact mechanism of action of luliconazole is unknown, but it is postulated to involve altering the synthesis of fungi cell membranes.
Luliconazole cream has been associated with some adverse reactions, including contact dermatitis and cellulitis, which have been reported during postmarketing use. If you experience skin irritation or rash while using Luliconazole cream, wash the affected area with plenty of soap and water.
